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HCV Advocate
HBV Advocate


Monday, January 16, 2012

Researchers Discover Means for Blocking Hepatitis C Infection

Researchers in Canada have discovered a new approach to blocking infection from the hepatitis C virus in the liver that could lead to new therapies.

HCV requires fat to replicate, and a team of scientists at the University of British Columbia have developed an inhibitor that decreases the size of host fat droplets in liver cells and stops the virus from multiplying and infecting other cells.

"Human Subtilase SKI-1/S1P Is a Master Regulator of the HCV Lifecycle and a Potential Host Cell Target for Developing Indirect-Acting Antiviral Agents." 
Olmstead AD , Knecht W , Lazarov I , Dixit SB , Jean F , 2012 Human Subtilase SKI-1/S1P Is a Master Regulator of the HCV Lifecycle and a Potential Host Cell Target for Developing Indirect-Acting Antiviral Agents. PLoS Pathog 8(1): e1002468. doi:10.1371/journal.ppat.1002468


Read the article here:

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