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HCV Advocate
HBV Advocate


Saturday, October 15, 2011

Gene variant that helps hepatitis C treatment may hinder HIV treatment

A common variant in a gene that doubles the chance of hepatitis C treatment working in people coinfected with HIV may also nearly double the risk of death in patients taking antiretroviral therapy.

A study from Poland found that patients with the so-called 'CC' variant of mutation site rs 1979860 of the IL28B gene were 80% more likely to die during follow-up than patients with the other two possible variants, CT and TT (the letters refer to the particular bases, cytosine and thymine, at that point in the DNA molecule).

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