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Alan Franciscus
HCV Advocate

Wednesday, August 24, 2011

Pharmasset receives fast track designation for Hep C drug PSI-938

PSI-938 inhibits the Hep C virus, as the drug's composition is similar enough to the structural make up of genetic molecules, allowing it to be easily incorporated into a growing strand of DNA. From there, it acts as a chain terminator, stopping the viral DNA from reproducing.

In March, Pharmasset presented the results of a 14-day study of PSI-938, which revealed strong anti-viral activity and safety and tolerability, both as a stand-alone treatment as well as in combination with the company's PSI-7977, also an inhibitor of viral DNA.

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