A combination of entecavir with Truvada is an effective and safe option for HIV/hepatitis B-co-infected patients whose current therapy is not suppressing hepatitis B viral load, investigators from the north of England report in the online edition of AIDS.
“Our study shows that this combination in co-infected patients appears safe and has efficacy, with reductions in HBV [hepatitis B virus] DNA and nearly 40% achieving an undetectable viral load in just over a year,” comment the investigators, who emphasise that their patients had extensive experience of hepatitis B therapy.
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